Injection-Free Compounded Semaglutide

Daily oral semaglutide gel absorbed through the cheek, starting at $199/mo

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Transparent plan pricing includes all medication
Monthly
$399
$199 /1st month
$199 the first month, then $399/mo
4-Month
$249 /mo
Billed as $996 every 4 months
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Compounded Semaglutide Gel Taken Orally
Painless and Needle-Free
Absorbed Between The Cheek and Gums
3 Minutes A Day
Is All It Takes
This is a compounded drug that has not been approved by the FDA for safety, effectiveness, or quality. The processes by which the compounded drugs are manufactured have not been reviewed by the FDA, and FDA-approved products containing semaglutide are available. CheekyMD's compounded medications are carefully prepared by our licensed pharmacists following strict safety and quality standards. The medications are designed using products sourced from FDA approved wholesalers.

Introducing CheekyMD

CheekyMD offers a unique compounded semaglutide gel applied inside your cheek for faster, more effective absorption. Unlike traditional tablets that lose potency in the stomach, our gel goes straight into your bloodstream—no injections needed.

Compounded medications are custom-made by licensed pharmacists to suit your specific needs. Our pharmacy partners meet PCAB and ACHC standards for top-tier safety, quality, and precision in every dose.

Why deliver medication via the buccal (cheek) pocket? Absorbing through the cheek bypasses the stomach, delivering more of the active ingredient directly into your bloodstream for quicker, more potent results.
SEMAGLUTIDE HAS BEEN FEATURED IN
WSJThe New York TimesREUTERSNBCFOX NEWSTHE OPRAH MAGAZINE
WSJThe New York TimesREUTERSNBCFOX NEWSTHE OPRAH MAGAZINE

What Our Customers Are Saying

Innovative Compounded Semaglutide Treament

Compounded buccal semaglutide,
administered in a needle-free form.

Compounded Semaglutide
Compounded medications with semaglutide requires the use of the same ingredient that is also a component of Wegovy® & Ozempic®, FDA-approved drugs.
Tastes Great
CheekyMD is formulated with a pleasant mint flavor, making your daily dose a pleasant experience.
Rapid Action
Absorbed directly into the bloodstream via the buccal membrane, bypassing the digestive system entirely.2
High Bioavailability
Buccal absorption provides superior bioavailability over oral pills​​.2
Completely Painless
No painful injections. Just a once-a-day dose dispensed directly into the cheek.
Stable Formulation
Semaglutide suspended in SubMagna™ HMW gel absorbs quickly into your system.2
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Needle-Free Compounded Semaglutide

Direct Bloodstream Absorption
Absorbed through the buccal lining of your cheek, the medication bypasses the digestive system for rapid and efficient delivery.1
Enhanced Stability and Absorption
The buccal region’s neutral pH and low enzymatic activity ensure maximum drug stability and absorption.1
Buccal Administration
The compounded semaglutide gel is administered in the buccal cavity, in between the cheek and gums.1

The CheekyMD Process

Fast, easy, and delivered right to your doorstep.

Fill out Form

We’ll ask a few questions
about your medical health

Select your Plan

Choose from monthly or multi-month plan options to save

Prescription Approved

A licensed medical provider virtually reviews and approves your prescription

Receive Medication

Your medication is delivered right to your door, shipping on us!

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How to Use

CheekyMD’s pain-free daily oral semaglutide applicators are easy to use, and taste good too!

Shake oral applicator for several seconds.

Dispense gel inside of your cheek.

Hold for 2-3 minutes, spit out and you’re done! Rinsing is optional.

Trusted Pharmacy Partners

Meeting and Exceeding Quality Standards
Our pharmacy partners are accredited by URAC, NABP, and ACHC, delivering top-tier care across the U.S., including PCAB and ACHC Rare Disease certifications.
Produced in Certified, Sterile Labs
CheekyMD semaglutide is produced in sterile, licensed labs, following strict accreditation standards.
Rigorous, Randomized Potency Testing
Our pharmacy partners conduct randomized, skip-lot potency testing to ensure our product meets the highest standards of strength, effectiveness, and consistency.

CheekyMD:

Compounded Semaglutide Without The Needle

CheekyMD’s pain-free daily oral semaglutide applicators are easy to use, and taste good too!

Helpful & Personalized Support
Cancel Anytime
Cancel Anytime
No Hidden Fees

Choose your plan

Starting at under $9 per day

MONTHLY PACK
$399
$199/ to start
$199 1st month special
28 doses of Buccal Semaglutide Medication
Regular medical check-ins
Unlimited support
Medication-related supplies
Free overnight shipping
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4-MONTH PACK
$249/ month
billed as $996 every 4 months
112 doses of Buccal Semaglutide Medication
Regular medical check-ins
Unlimited support
Medication-related supplies
Free overnight shipping
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The CheekyMD Process

Fast, easy, and delivered right to your doorstep.
1
Complete the
pre-screen form
2
Select a plan that works best for you
3
Prescription approved by a doctor in our network
4
Receive your semaglutide with free shipping
GET STARTED

Frequently Asked Questions

What is oral compounded semaglutide?

Compounded medications are custom formulations created by licensed pharmacists according to a physician’s prescription for an individual patient. Unlike mass-produced medications, compounded drugs are tailored to meet specific patient needs, such as unique dosage forms or strengths. At CheekyMD, we partner with accredited pharmacies that follow the highest safety and quality standards. Our pharmacy partners are accredited by PCAB (Pharmacy Compounding Accreditation Board) and ACHC (Accreditation Commission for Health Care) for Rare Disease, and they conduct randomized, skip lot potency testing to ensure the consistency and effectiveness of every batch. Additionally, all ingredients are sourced from FDA-registered wholesalers.

Compounded oral semaglutide specifically refers to semaglutide, a clinically proven medication for long-term weight management, formulated as an easy-to-take oral gel. This form of semaglutide is absorbed through the cheek (buccal administration), bypassing the digestive system for better bioavailability. It offers a needle-free alternative for individuals looking to manage their weight with a well-established active ingredient, while receiving personalized care and support through CheekyMD’s telehealth platform.

Is CheekyMD’s gel-based method safe?

Absolutely! Our gel-based method is completely safe and is designed to offer improved bioavailability and a rapid onset of action without the need for injections. Although it's completely safe if you swallow a little during the 3 minutes, it is not intended to be swallowed. At the end of the 3 minutes you should spit out any remaining medication.

By bypassing the digestive system, this form of delivery reduces common gastrointestinal side effects seen in other oral versions of semaglutide.1

How effective is semaglutide?

CheekyMD gel contains compounded semaglutide, a powerful active ingredient in weight management treatments. In clinical studies, semaglutide has been shown to help individuals with a BMI of 30 or more, or 27 or more with at least one weight-related health condition, lose an average of 14.9% of their body weight over approximately 68 weeks.2

Does the cost include medication?

Yes, it does! Our comprehensive pricing includes everything you need—medication (all dosage levels!), shipping, personalized support, and ongoing medical consultations. No hidden fees whatsoever!

How long will it take to lose weight?

Results can vary depending on individual factors, but studies on semaglutide show that participants typically experience significant weight loss over a period of 68 weeks. On average, individuals with a BMI of 30 or more, or 27 or more with related health conditions, lost around 14.9% of their body weight.2

What makes CheekyMD a reliable and trusted service?

Absolutely! CheekyMD partners with accredited pharmacies that perform rigorous potency testing to ensure the highest quality of medication. If you’re not medically approved by a licensed physician in our network, you'll receive a full refund promptly. Plus, you can cancel anytime. Our compounded semaglutide is crafted with the same active ingredient used in leading FDA-approved weight management therapies, reflecting our commitment to safe and effective treatment.

1. Evaluation of the Absorption of a Sublingual Semaglutide Compounded Formulation (Technical Report)
‍2. In a clinical trial (NEJM), participants with a BMI of 30 or more, or 27 or more with at least one weight-related condition, lost an average of 14.9% of their body weight during the 68-week trial.